Isotopically Labeled Compounds
![Revvity Health Sciences Inc Thymidine, [Methyl-<sup>3</sup>H]-, Specific Activity: 6.7 Ci/mmol, 250µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502810533.jpg-250.jpg)
Revvity Health Sciences Inc Thymidine, [Methyl-3H]-, Specific Activity: 6.7 Ci/mmol, 250µCi
Thymidine, [Methyl-3H]-, Specific Activity: 6.7 Ci/mmol, 250µCi
Cayman Chemical DL-Aspartic Acid-d3, Purity: ≥99% deuterated forms (d1-d3), CAS: 14341-75-4, 10 mg
An internal standard for the quantification of aspartic acid by GC- or LC-MS
Cayman Chemical nor-W-18-d4, Purity: ≥99% deuterated forms (d1-d4), CAS: 2701349-29-1, 1 mg
An internal standard for the quantification of nor-W-18 by GC- or LC-MS; intended for research and forensic applications
Cambridge Isotope Laboratories ACETANILIDE (D8, 98%), 1 G, 22778-17-2
ACETANILIDE (D8, 98%), 1 G, 22778-17-2
Medchemexpress LLC Crizotinib-d5 | 1395950-84-1 | 99.6% | C₂₁H₁₇D₅Cl₂FN₅O | 1 MG
Crizotinib-d5 is the deuterium labeled version of Crizotinib. Crizotinib functions as an orally bioavailable, ATP-competitive inhibitor targeting ALK and c-Met, with IC50s of 20 nM and 8 nM, respectively. It effectively inhibits tyrosine phosphorylation of NPM-ALK and c-Met in cell-based assays, exhibiting IC50s of 24 nM and 11 nM. Crizotinib also acts as a ROS1 inhibitor and demonstrates effective tumor growth inhibition.
- Deuterium labeled crizotinib.
- Orally bioavailable.
- Functions as an ATP-competitive ALK and c-Met inhibitor.
- Inhibits tyrosine phosphorylation of NPM-ALK and c-Met in cell-based assays.
- Acts as a ROS1 inhibitor.
- Demonstrates effective tumor growth inhibition.
- Suitable for use as a tracer.
- Can serve as an internal standard for quantitative analysis using methods like NMR, GC-MS, or LC-MS.
Medchemexpress LLC 1,3,5-triazine-2,4,6-triamine-13C3 | 1173022-88-2 | MFCD12546054 | 98.7% | 129.10 | 13C3H6N6 | 10mg
Melamine-13C3 is the 13C labeled Melamine[1] Melamine is a metabolite of cyromazine Melamine is a intermediate for the synthesis of melamine resin and plastic materials[2]
Medchemexpress LLC 1-methyladenosine-d3 | 00-00-0 | 284.29 | C11H12D3N5O4 | 5 MG
1-Methyladenosine-d3 is the deuterium-labeled form of 1-methyladenosine supplied as a stable isotope research standard. It is used as an internal standard and tracer in LC-MS/MS and metabolic studies of RNA modifications and nucleoside metabolism. The product is provided with supporting documentation for analytical use.
- Deuterium-labeled internal standard for quantitative mass spectrometry.
- Suitable for LC-MS/MS method development and validation.
- Supports studies of RNA modification and nucleoside metabolism.
- Supplied with datasheet, SDS, and certificate of analysis.
- Available in small-mass quantities for analytical use.
Medchemexpress LLC Maleic acid-d2 | 24461-33-4 | 99.3% | 118.08 | C4H2D2O4 | 50mg
Maleic Acid-d2 is the deuterium labeled Maleic Acid[1] Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E coli and L monocytogenes[2][3]
Medchemexpress LLC D-Alanine-d3 | 177614-69-6 | 99.31% | 92.11 | 5 MG
D-Alanine-d3 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC DL-glutamic acid-d5 | 14341-79-8 | MFCD01074021 | 99.7% | 152.16 g/mol | C5H4D5NO4 | 5 MG
DL-glutamic acid-d5 is the deuterium-labeled analogue of DL-glutamic acid used as an isotope-labeled standard in mass spectrometry and metabolite analysis. It is supplied as a pre-weighed solid for analytical applications.
- deuterium-labeled internal standard for mass spectrometry.
- high purity (99.7%).
- molecular weight 152.16 g/mol.
- molecular formula C5H4D5NO4.
- available as pre-weighed vials (e.g., 5 MG).
Medchemexpress LLC Fenoverine-d8 | 00-00-0 | MFCD00865242 | 98.9% | 467.61 g·mol⁻1 | C26H17D8N3O3S | 10 MG
Fenoverine-d8 is a deuterium-labeled analytical standard of fenoverine used as a stable isotope internal standard in quantitative LC-MS and other analytical assays. It is provided with high purity and defined molecular properties for method development, validation, and pharmacokinetic or bioanalysis studies.
- Deuterium-labeled internal standard for LC-MS quantitation.
- High purity suitable for analytical applications.
- Characterized molecular weight and formula for accurate identification.
- Available in multiple small package sizes for method development.
- Provides improved accuracy in pharmacokinetic and bioanalysis studies.
Cayman Chemical Candesartan-d4, Purity: ≥99% deuterated forms (d1-d4), CAS: 1346604-70-3, 5 mg
An internal standard for the quantification of candesartan by GC- or LC-MS
Medchemexpress LLC L-Lysine-15N dihydrochloride | 204451-50-3 | > 98.0% | 220.10 | 1 MG
L-Lysine-15N dihydrochloride is a 15N-labeled L-Lysine dihydrochloride, primarily utilized as a tracer for quantitation in drug development processes. This compound incorporates stable heavy isotopes of hydrogen, carbon, and other elements for research applications.
- 15N-labeled L-Lysine dihydrochloride
- Suitable for research use only
- Store at 4°C, sealed, and away from moisture
- For solutions, store at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Fmoc-Pro-OH-13C5,15N | 1217452-48-6 | MFCD08702954 | 98.0% | 343.33 | 100 MG
Fmoc-Pro-OH-13C5,15N is a 15N-labeled and 13C-labeled Fmoc-Pro-OH, a proline derivative. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- 15N-labeled and 13C-labeled compound.
- Proline derivative.
- Used as tracers for quantitation during drug development.
- Relevant for studies on pharmacokinetic and metabolic profiles of drugs.
- Targeted for fungal and isotope-labeled compounds.
- Applicable in anti-infection and other pathways.